Volume 30 - Article 10 | Pages 313–332  

Heterogeneity's ruses: How hidden variation affects population trajectories of age-dependent fecundity in Drosophila melanogaster

By Aziz Khazaeli, James Curtsinger

References

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Curtsinger, J.W., Gavrilova, N.S., and Gavrilov, L.A (2006). Biodemography of aging and age-specific mortality in Drosophila melanogaster. In: Masoro, E.J. and Austad, S.N. (eds.). Handbook of the biology of aging. Amsterdam: Elsevier Academic Press.

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Curtsinger, J.W. and Khazaeli, A.A. (2002). Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila. Mechanisms of Ageing and Development 123(2–3): 81-93.

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Khazaeli, A.A. and Curtsinger, J.W. (2010). Life history variation in an artificially selected population of Drosophila melanogaster: Pleiotropy, superflies, and age-specific adaptation. Evolution 64(12): 3409-3416.

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Khazaeli, A.A. and Curtsinger, J.W. (2013). Pleiotropy and Life History Evolution in Drosophila melanogaster: Uncoupling Life Span and Early Fecundity. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 68(5): 546-553.

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Khazaeli, A.A., Pletcher, S.D., and Curtsinger, J.W. (1998). The fractionation experiment: reducing heterogeneity to investigate age-specific mortality in Drosophila. Mechanisms of Ageing and Development 105(3): 301-317.

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Rauser, C.L., Abdel-Aal, Y., Shieh, J.A., Suen, C.W., Mueller, L.D., and Rose, M.R. (2005a). Lifelong heterogeneity in fecundity is insufficient to explain late-life fecundity plateaus in Drosophila melanogaster. Experimental Gerontology 40(8–9): 660-670.

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Rauser, C.L., Hong, J.S., Cung, M.B., Pham, K.M., Mueller, L.D., and Rose, M.R. (2005b). Testing whether male age or high nutrition causes the cessation of reproductive aging in female Drosophila melanogaster populations. Rejuvenation Res 8(2): 86-95.

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Vaupel, J.W., Carey, J.R., Christensen, K., Johnson, T.E., Yashin, A.I., Holm, N.V., Iachine, I.A., Kannisto, V., Khazaeli, A.A., Liedo, P., Longo, V.D., Zeng, Y., Manton, K.G., and Curtsinger, J.W. (1998). Biodemographic Trajectories of Longevity. Science 280(5365): 855-860.

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