Volume 18 - Article 9 | Pages 263–284

Cohort fertility patterns and breast cancer mortality among U.S. women, 1948-2003

By Patrick M. Krueger, Samuel H. Preston

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Date received:02 Jan 2008
Date published:15 Apr 2008
Word count:4963
Keywords:age-period-cohort models, breast cancer mortality, cohort fertility


Epidemiological research has shown that women who have early and numerous births have reduced risks of being diagnosed with breast cancer. We use U.S. Vital Statistics and Census data and age-period-cohort models to examine whether cohort fertility patterns are associated with breast cancer mortality rates among women aged 40 and older in 1948-2003. Cohorts marked by higher proportions childless at ages 15-24 and lower cumulative second birth rates at ages 15-29 have higher rates of breast cancer mortality. This is the first demonstration that cohort fertility patterns have left a clear imprint on trends in U.S. breast cancer mortality rates.

Author's Affiliation

Patrick M. Krueger - University of Texas Health Science Center at Houston, United States of America [Email]
Samuel H. Preston - University of Pennsylvania, United States of America [Email]

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